diff --git a/tests/v1/distributed/test_eagle_dp.py b/tests/v1/distributed/test_eagle_dp.py
index f62e85dcd..1b7c2d8ea 100644
--- a/tests/v1/distributed/test_eagle_dp.py
+++ b/tests/v1/distributed/test_eagle_dp.py
@@ -51,7 +51,6 @@ async def test_run_eagle_dp(monkeypatch: pytest.MonkeyPatch):
     # https://github.com/vllm-project/vllm/issues/31913
     num_expected_tokens = 20
     sampling_params = SamplingParams(
-        min_tokens=num_expected_tokens,
         max_tokens=num_expected_tokens,
         ignore_eos=True,
         output_kind=RequestOutputKind.FINAL_ONLY,
diff --git a/vllm/v1/engine/input_processor.py b/vllm/v1/engine/input_processor.py
index 8275dc409..5af808c82 100644
--- a/vllm/v1/engine/input_processor.py
+++ b/vllm/v1/engine/input_processor.py
@@ -19,7 +19,7 @@ from vllm.multimodal.parse import MultiModalDataParser
 from vllm.multimodal.processing import EncDecMultiModalProcessor, set_request_id
 from vllm.multimodal.utils import argsort_mm_positions
 from vllm.pooling_params import PoolingParams
-from vllm.sampling_params import SamplingParams
+from vllm.sampling_params import _SAMPLING_EPS, SamplingParams
 from vllm.tokenizers import TokenizerLike
 from vllm.tokenizers.mistral import MistralTokenizer
 from vllm.utils import length_from_prompt_token_ids_or_embeds, random_uuid
@@ -153,8 +153,18 @@ class InputProcessor:
         # Logits processors not supported.
         if params.logits_processors:
             raise ValueError(
-                "vLLM V1 does not support per request user provided logits processors."
+                "vLLM V1 does not support per request user-provided logits processors."
             )
+
+        # Some sampling parameters are not yet compatible with spec decoding.
+        if self.vllm_config.speculative_config is not None and (
+            params.min_tokens > 1 or params.min_p > _SAMPLING_EPS or params.logit_bias
+        ):
+            raise ValueError(
+                "The min_tokens, min_p, and logit_bias sampling parameters "
+                "are not yet supported with speculative decoding."
+            )
+
         # Async scheduling + spec decode currently incompatible with some
         # sampling parameters.
         if (